Kate Coldwell

Experience

• 

  La Trobe University

  Feb 2003 - Nov 2007

  Doctoral Student

  Doctoral research project on the anti-cancer effect of Adriamycin (doxorubicin)-DNA adducts. -showed the effectiveness of Adriamcyin in combination with formaldehyde-releasing prodrugs-proved the clinical relevance of drug-DNA adducts as a mechanism of action of Adriamycin-developed a new ultrasensitive method for detection of Adriamcyin-DNA adducts at clinically-relevant levels never achieved before.

• 

  NHS Blood and Transplant

  Jan 2008 - Jul 2011

  Investigated the potential of umbilical cord blood-derived endothelial progenitor cells for tissue engineering.• Assessed the potential of stem cells from umbilical cord blood for repairing damaged blood vessels.• Optimised cryopreservation of human umbilical cord blood for endothelial colony-forming cells.• Correlated endothelial progenitor cells from cord blood and correlated them with obstetric factors such as multiple births, sex of baby, type of birth. • Administered a UK-wide research resource providing human placental tissues such as cord blood, placenta and umbilical cord to 25 research groups across the UK.• Increased client base by 300% in 3 years • Supervised a team of technicians and research students working on human umbilical tissues.

  • Postdoctoral Research Scientist

    May 2008 - Jul 2011

  • Placental Biobank Manager

    Jan 2008 - Jan 2011
• 

  University of Oxford

  Feb 2008 - May 2008

  Postdoctoral Research Assistant

  Oxford Experimental Cancer Medicine Centre, Oxford UniversityInvestigated signs of anti-angiogenic activity in serum samples from cancer clinical trials.• Documented, cryopreserved, catalogued and archived samples • Optimised and authored standard operating procedures for ELISA-based biomarker measurement • Assayed samples contributing vast clinical trial data sets to trials. • Authored a study report to stakeholders.

• 

  University of Oxford

  Jul 2011 - Sept 2011

  Postdoctoral Research Assistant

  Oxford Experimental Cancer Medicine Centre, Oxford UniversityInvestigated signs of anti-angiogenic activity in serum samples from cancer clinical trials.• Documented, cryopreserved, catalogued and archived samples • Optimised and authored standard operating procedures for ELISA-based biomarker measurement • Assayed samples contributing vast clinical trial data sets to trials. • Authored a study report to stakeholders.

• 

  Oxford Cancer Biomarkers

  Jun 2012 - Feb 2014

  Cancer Biomarker Scientist

  Oxford Cancer Biomarkers works hand-in-hand with partner companies to provide companion biomarker diagnostic tests that help target the drug to responsive patients.• Industry role discovering cancer biomarkers in partnership with pharmaceutical companies• Discovered companion diagnostics for cancer treatments

• 

  Thameside Primary School

  Mar 2014 - Sept 2014

  Teaching Assistant

  Supporting a Year 3 teacher with students with special educational needs.

• 

  Didcot Girls'​ School

  Jul 2015 - Aug 2023

  -Certified Microsoft Innovative Educator-mobilised staff digital champions, pandemic remote teaching strategy and student peer digital champions-conceived vision of school-wide digital teaching and learning -orchestrated staff needs analysis and responded with needs-adapted training bites Didcot Girls' School is the only all girls' comprehensive school in Oxfordshire. It has been rated Ofsted Outstanding since 2016. My roles include:-teaching Science and Computing to Key Stage 3 -leading Key Stage 3 Computing-teaching Chemistry, Physics and Biology to Key Stage 4-teaching Chemistry to Key Stay 5 (A-level)-mentoring trainee teachers and pastoral tutors

  • Digital Strategy Lead

    Jan 2019 - Aug 2023

  • Secondary School Teacher

    Jul 2015 - Aug 2023
• 

  Oxford University Press

  Sept 2023 - now

  Freelance Author
• 

  Kennedy Institute of Rheumatology

  Jul 2024 - now

  Daphne Jackson Fellow

  Kate’s project is to understand further the relationship between the liver, the gut, and the gut microbiome and how this is impacted by liver disease. The title of her project is: Disentangling the temporal interplay between the liver and gut in primary sclerosing cholangitis Kate’s Fellowship is sponsored by The Kennedy Trust for Rheumatology Research and the Medical Research Council (MRC).