
Chaitanya Kedari
Research Associate

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About me
Senior Manager at Biological E. Limited, MSAT- Downstream process, Technology transfer, Vaccines, Proteins, Biosimilars, Peptides Complex generics and Qualified Lean six sigma black belt
Education

Sri Ramachandra Medical College and Research Institute
2007 - 2009Masters Medicinal ChemistryActivities and Societies: 1.Stood first in class in M.Sc. Medicinal chemistry. 2. Memorial GOLD MEDAL in B Pharm for performance in Biotechnology paper. Feb 2008: Attended “Chemophile” and presented a poster onROLE OF CHELATES IN TREATMENT OF CANCER and won 2nd prize held at Gurunanak College, Chennai

Sri Ramachandra Medical College and Research Institute
-Masters Medicinal and Pharmaceutical Chemistry
Andhra University
2002 - 2006B. pharmacy Pharmaceutical Sciences
Experience

AstraZeneca R&D
Nov 2009 - Feb 2013Research AssociateSynthesis of NCE's in Drug discovery Department, Building of SAR by bringing the potency to make a Lead molecule.

Alkem Laboratories Ltd.
Feb 2013 - Dec 2013Research ScientistChemical synthesis of NCE's, Purification and submission for the biological studies. Problem solving in Chemistry, writing novel chemsitry routes. Building of SAR of the molecules.

Dr. Reddy's Laboratories
Jan 2014 - Jan 2019Impurities isolation and characterization of the peptides, optimization of the purification process using DoE for scale up purification. Peptide Purification By RP-HPLC, Scale Up in Purification. Isolation of peptides from Fermentation media by Extraction, titruration, column chromatography. Method development by HPLC. Identification and isolation of impuritiesSythesis of final compounds, scale up and purification of the final compounds. Analysis of the reactions using Mass spec and structure confirmation by other techniques.
Scientist
Jan 2017 - Jan 2019Assistant Manager
Jan 2014 - Dec 2016

Virchow Biotech private limited
Jan 2019 - Jan 2020ManagerDownstream Process HeadDevelopment of Downstream Process of Fermenatation Based products.Process Optimisation of Downstream Process of Peptides and ProteinsPurification Process optimization, scale up parameters and technology transfer of Peptides and Biosimilars

Biological E. Limited
Feb 2020 - nowDownstream process of viral and bacterial vaccine development, Technology transfer process expert of biologics, vaccines (mRNA technology, JE, HPV, Bivalent conjugate vaccine, and Polio VLP), and peptides. Knowledge in the manufacturing process of Heparin sodium and Enoxaparin Process development of Viral and Bacterial Vaccines, involved in process development of CoVid vaccine , Conjugation of Glyco-protein in vaccines, applying QbD tools to the existing projects for process optimisation.
Senior Manager
Feb 2020 - nowManufacturing Manager
Feb 2020 - May 2022
Licenses & Certifications
- View certificate

Certified Lean Six Sigma Green Belt
VarSigma ConsultingSept 2018 - View certificate

Certified Lean Six Sigma Black Belt
VarSigma ConsultingJun 2019
Languages
- enEnglish
- teTelugu
- hiHindi
- taTamil
- kaKannada
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