Bharghavi Balaji

Experience

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  Dayananda Sagar College of Engineering, BANGALORE

  Jan 2018 - Jun 2021

  Event Management
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  Azyme Biosciences

  Jun 2019 - Jul 2019

  Internship Trainee, Enzymology

  To demonstrate the effect of change in incubation time of enzyme activity.• Worked with protease and amylase enzyme using two different types of fermentation purification methods (submerged and solid-state fermentation) to demonstrate process optimisation effects.

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  RV College Of Engineering

  Aug 2020 - Sept 2020

  Intern, Computational Drug Discovery

  In-silico screening on Phyto compounds as prospective anti-cancer drugs targeting WNT signaling pathway against Triple Negative Breast Cancer(TNBC)• Led a team of four in a project focused on identifying and evaluating phytocompounds as potential anti-cancer drugs targeting the WNT signaling pathway in Triple Negative Breast Cancer (TNBC).• Developed a deep understanding of the mechanisms underlying TNBC and the potential of natural compounds to address this challenging disease.• Leveraged bioinformatics tools and molecular modeling techniques to conduct computational virtual screening and identify promising drug candidates.Gained hands-on experience with Autodock, PyRX, PyMOL, and Avogadro to perform molecular docking and ADMET studies on selected ligands. Show less

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  Anthem Biosciences Private Limited

  Sept 2021 - Dec 2021

  Project Intern, Upstream Fermentation

  • Increased biomass yield by 20% and reduced cultivation time by 30% through the development and implementation of innovative growth strategies for cloned fungal and recombinant bacterial cultures under GMP guidelines.• Enhanced product quality and reduced contamination by 10% by collaborating with cross-functional teams to troubleshoot and resolve upstream fermentation process challenges.• Achieved substantial improvement in cell growth and productivity by optimizing media and feed composition for bioreactor cultures through rigorous process optimization techniques. Show less