Mareike Giefer

Experience

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  TU Darmstadt

  Sept 2011 - Jun 2013

  Presentation coach
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  Julius Kühn-Institut

  Jul 2012 - Sept 2012

  Research Intern
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  Merck Serono

  Jun 2014 - Aug 2014

  Research Intern

  Within the department ImmunoOncology - Emerging Immunotherapies of Merck Serono I worked on the characterization of immune cell lines and the development of high-throughput screenings. In order to achieve this, the following procedures were performed:- Cultivation of immune cell lines and analyzation of the growth patterns and morphology - Characterization of the surface expression profile of immune cell lines after cell activation by flow cytometry (FACS)- Analysis of the cytokine production of immune cell lines in an ELISA Show less

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  Merck Serono

  Oct 2014 - Jun 2015

  Master Student

  Within the department Protein Engineering and Antibody Technologies of Merck Serono I worked on my master thesis with the title 'Biochemical characterization of monovalent antibody derivatives with therapeutic potential'.The following procedures were performed: - Transient expression of antibodies in Expi293F cells- Purifcation and quality control of the expression quality by SEC and HPLC - Characterization of the binding kinetics between the therapeutic antibody derivatives and their antigen by BLI (bio-layer-interferometry)- Identification of the potential of the antibody derivatives to inhibit ligand binding and the phosphorylation of the antigen by ELISA and Western Blot analyses - Analysis of the potential to inhibit cell proliferation and migration of tumor cell lines Show less

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  Mibeg-Institut Medizin

  Jun 2016 - Aug 2016

  Trainee Clinical Research

  Training to Clinical Research Associate (clinical research trainee).- Clinical examination and evaluation of drugs, medical statistics and biometrics- Basics of national and international pharmaceutical laws / ICH-GCP - Medical basics and medical terminology, pharmacological / toxicological basics- Communication training- Business English - Economy of the pharmaceutical industry - Project management- Computer applications in clinical trials

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  National Center for Tumor Diseases (NCT) Heidelberg

  Sept 2016 - Feb 2017

  Research Associate
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  Linical

  May 2017 - Oct 2017

  Clinical Trial Associate
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  Fresenius Medical Care

  Nov 2017 - Jun 2021

  • Manager Clinical Research

    Jul 2019 - Jun 2021

  • Junior Manager Clinical Research

    Nov 2017 - Jun 2019
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  AstraZeneca

  Sept 2021 - Apr 2023

  Therapy Area Specialist
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  AstraZeneca

  Jul 2024 - now

  Medical Science Liaison