Abu Nahid

Experience

• 

  Libra pharmaceuticals Ltd

  Jan 2001 - Sept 2002

  Quality Control Microbiologist

  • Quality control of intravenous infusions followig USP and BP in an ISO 9001 certified industry• LAL, endotoxin, sterility test, and bacterial analysis of bulk pharmaceutical raw materials, in process, and finished sterile products• cGMP and environmental monitoring

• 

  Osaka Prefecture University

  Oct 2002 - Sept 2006

  Graduate Research Assistant

  • Isolation and purification of GlcNAc-binding animal serum protein• Generation of rabbit polyclonal antibody against animal IgG and IgM • Generation and characterization of mouse monoclonal antibody (hybridoma) against animal serum protein with a view to developing therapeutic against infectious animal diseases• Develop immune e assay to detect anti-microbial serum protein and stress-induced serum protein• Molecular identification of clinically important animal pathogens • Investigate the biological significance of anti-microbial protein in innate immunity in terms of binding and killing of various Gram-positive and Gram-negative bacteria Show less

• 

  University of Florida

  Aug 2007 - Aug 2011

  Graduate (Ph.D.) Research Assistant

  • Molecular and immunological approach to study MicroRNA and immunity• Examine the mechanistic role of TLR ligands-induced microRNAs (miR-146a, miR-132, and miR-212) to regulate the overproduction of pro-inflammatory mediators during microbial infection• Investigate the mechanistic role of cytokine-induced miRNA to prevent tissue damage• Investigate the microRNA associated inflammatory and autoimmune diseases• Use of microRNA as a therapeutic intervention against inflammatory diseases Show less

• 

  Stanford University

  Sept 2011 - Sept 2012

  Post-doctoral Research Fellow

  • Immunological approach to study the immunobiology of ES cells and iPS cells transplantation • Investigation the beneficial impact and mechanism of action of costimulatory blockers (such as CTLA4-Ig, Anti-CD40L, Anti-LFA, Anti-VLA4) to prevent the immunological rejection of transplanted stem cells• Gene therapy for ishemic heart diseases using minicircle DNA

• 

  University of Massachusetts

  Oct 2012 - May 2013

  Postdoctoral Research Fellow

  • Gene therapy research with special interest to develop an improved HIV/AIDS vaccine• Molecular and immunological approach to understand the transgene immunity and evasion mechanism of cross-presentation leading to vaccine development• In vitro and in vivo immunological assays development (ELISA and CTL)

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  Merck

  Jun 2013 - Jun 2015

  Associate Scientist (Immunolgy, Oncology and IMR Discovery Research)

  • Generation of hybridoma (rabbit monoclonal antibody) against immune targets and screening with the aim to develop biologics against autoimmune diseases• Target identification and validation for early drug discovery linked to autoimmune and immune deficient disease• Magnesium probe development • Small molecules screening in patient cell line leading to drug development• Investigate the molecular mechanism of microRNAs (miR-146a and miR-23b) function that implicate in proinflammatory mediator release by innate immune cells (monocyte, macrophage, and dendritic cells) and T lymphocyte • Generation of CRISPR knock out T cell line • Investigate the novel mechanism of T lymphocyte functional defect in primary immunodeficient patient (XMEN) using RNAseq and PTMScan analysis (system biology approach)• Pharmacokinetic-Pharmacodynamic (PK/PD) concept in clinical research Show less

• 

  US Army

  Jul 2015 - now

  • Oversee and manage clinical microbiology laboratory operation for moderate and high complexity testing in a CLIA-certified Microbiology laboratory • The Bacteriology, Virology/Immunology, Parasitology, Tuberculosis, and Mycology analysis of clinical specimens and interpreting the test results• Bio threat agent detection, laboratory response network (LRN), biosafety effort, and clinical bio preparedness• Conduct, facilitate, and oversee activities related to the inspection of clinical laboratories• Conduct laboratory quality control (QC), Individualized Quality Control Plan (IQCP) development, verification/validation of diagnostic instrument, and CAP proficiency testing• Provide lectures on microbiology/immunology to infectious disease physicians• Monitor the lab test use and cost trends and perform economic analyses of best test usage per Clinical Practice Guidelines to support Department of Defense (DoD) beneficiaries• Broad research expertise focusing on disease surveillance, Infectious diseases and associated molecular diagnostics Show less • Lead, supervise, evaluate, and provide technical guidance to the personnel to conduct research for optimizing combat casualty care• Responsible for developing collaboration with other US military and civilian research entities to support USAISR and MRDC mission• Responsible for cost, schedule, and performance of DoD funded projects for Research, Development, Test, and Evaluation (RDT&E)• Perform research focusing on open wound & burn infection as well as investigation of antimicrobials to diminish biofilm development in wound infection• Perform microbiological analysis of clinical samples, identification, sensitivity, and diseases surveillance• Serve as a subject matter expert for biosafety, bio-threat agents detection, clinical biopreparedness mission• Perform COVID-19 testing at Brooks Army Medical Center Show less • In CLIA-certified laboratory, process a wide range of clinical specimens, including but not limited to blood, urine, stools, exudates, tissues, and body fluids• Microbiological analysis (Bacteriology, Virology/Immunology, Parasitology, Tuberculosis and Mycology) of clinical specimens, antibiotics sensitivities and interpret of test results• Manage laboratory operation, provide consultation, and provide expert advice to health care providers • Serve as a member of the scientific review committee; assures that all research protocols meet Federal and Army regulation• Expert on validation of diagnostic technology, biothreat agents, biopreparedness, and diseases surveillance• Teach microbiology to the medical laboratory technologist students• Lead research focusing on nosocomial transmission, infectious diseases, wound infection, and application of various technologies (microarray, NGS, and MALDI TOF) for determining drug resistance organisms Show less

  • Deputy Chief, Infectious Diseases Lab (Clinical and Research Microbiologist)

    Apr 2021 - now

  • Chief, Dept. of Microbiology (Clinical & Research Microbiologist)

    Nov 2018 - Mar 2021

  • Chief, Virology & Immunology (Clinical Microbiologist)

    Jul 2015 - Oct 2018