Chun-Yi Lin

Experience

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  Institute of Biomedical Sciences, Academia Sinica

  Oct 2002 - Oct 2006

  Research Assistant (Team Leader)

  Study cell meiosis with cell biology protocols, such as Flow cytometry, Microinjection, Molecular cloning etc.Publication:Dynamic localization and functional implications of Aurora-C kinase during male mouse meiosis. Tang, C.J., Lin, C.Y., and Tang, T.K. (2006). Dev Biol 290, 398-410.

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  China Medical University Hospital

  Nov 2006 - May 2009

  Research Assistant (Team Leader)

  Built up the antibody core for cancer research in both MD Anderson Cancer Center and China Medical University Hospital.Publications:Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Hsu, J.M., Chen, C.T., Chou, C.K., Kuo, H.P., Li, L.Y., Lin, C.Y., Lee, H.J., Wang, Y.N., Liu, M., Liao, H.W., Shi, B., Lai, C.C., Bedford, M.T., Tsai, C.H., and Hung, M.C. (2011). Nat Cell Biol 13, 174-181.CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells. Wei, Y., Chen, Y.H., Li, L.Y., Lang, J., Yeh, S.P., Shi, B., Yang, C.C., Yang, J.Y., Lin, C.Y., Lai, C.C., and Hung, M.C. (2011). Nat Cell Biol 13, 87-94.The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription. Chou, C.K., Lee, D.F., Sun, H.L., Li, L.Y., Lin, C.Y., Huang, W.C., Hsu, J.M., Kuo, H.P., Yamaguchi, H., Wang, Y.N., Liu, M., Wu, H.Y., Liao, P.C., Yen, C.J., and Hung, M.C. (2009). Mol Carcinog 48, 1048-1058.Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer. Ding, Q., Huo, L., Yang, J.Y., Xia, W., Wei, Y., Liao, Y., Chang, C.J., Yang, Y., Lai, C.C., Lee, D.F., Yen, C.J., Chen, Y.J., Hsu, J.M., Kuo, H.P., Lin, C.Y., Tsai, F.J., Li, L.Y., Tsai, C.H., and Hung, M.C. (2008). Cancer Res 68, 6109-6117. Show less

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  Sinphar Pharmaceutical Co., Ltd.

  Jul 2014 - Oct 2016

  Quality Deputy Manager (Head)

  Assist to establish new factories. Guarantee a PIC/S GMP conformed Pharmaceutical.

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  Everlight Chemical

  Nov 2016 - Aug 2018

  Quality Assurance Manager (Head)

  Assure drug substance products to be manufactured and released under GMP compliance.

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  Genovior Biotech Corporation

  Sept 2018 - Jun 2019

  Director of Quality Assurance (Head)

  Assist to establish new factories. Assure biosimilar products in both of drug substance and drug product to be manufactured and released under GMP compliance.

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  Amaran Biotechnology, Inc.

  Jun 2019 - Aug 2020

  Senior Quality Assurance Manager (Head)

  Assist to establish a new factory. Assure biosimilar drug substance to be manufactured and released under GMP compliance.

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  Mycenax Biotech Inc.

  Sept 2020 - Nov 2021

  Senior Quality Assurance Manager (Head)

  Assist to establish new factories. Assure biosimilar products in both of drug substance and drug product to be manufactured and released under GMP compliance.

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  Locus Cell Co., Ltd

  Feb 2022 - now

  Senior Quality Assurance Manager (Head)

  Assist to establish a new factory. Establish a GMP compliant system for cell therapy factory.