Gráinne Dunlevy

Experience

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  Domantis

  Nov 2005 - Mar 2007

  Scientist I
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  GSK

  Mar 2007 - Aug 2014

  Senior Scientist
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  Crescendo Biologics Limited

  Aug 2014 - Apr 2018

  Protein Sciences and Protein Purification Group Leader

  • Established and managed the Protein Sciences and Purification Group. • Management of the team to achieve the purification, characterisation, protein engineering, formatting and chemical conjugation of therapeutic antibody fragments in preclinical development for immuno-oncology. • Project managed a Humabody® development project including leading a multidisciplinary team, deciding on the selection approach, characterisation and validation. Resulting in patent application WO2020229842• Set up high-throughput protein production for early in-format characterisation.• Writing of Candidate nomination documents for a drug candidate, forming part of the regulatory filing documents.• Production, engineering and design of bispecifics and multispecifics. Show less

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  Abcam

  Apr 2018 - Nov 2021

  Head of Protein Sciences

  Established the production for Abcam’s new product line “Premium Bioactive Proteins”. From lab set up and build to the launch of 30 new recombinant proteins, in a new market leading quality class, within 8 months.Increased the output of the recombinant protein immunogen pipeline through technology developments alone to increase output by 25%.Responsible for the delivery of proteins from the Protein Science teams in Cambridge, UK and Hangzhou, China. Develop and manage operating budgets. Lead a multi-disciplinary team, including molecular biology, protein expression, purification, and analytics in an ISO9001 accredited environment. Show less

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  Astrea Bioseparations Ltd

  Nov 2021 - Dec 2023

  R&D Director Delivery
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  BBI Solutions

  Feb 2024 - now

  Head of Research And Development