Stefanie Mullins

Stefanie Mullins

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location of Stefanie MullinsMilton Keynes, England, United Kingdom

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  • Timeline

  • About me

    Translational Sciences Lead | Project Lead | Immuno-oncology

  • Education

    • Wayne State University School of Medicine

      2000 - 2005
      PhD Cancer Biology

      Activities and Societies: Representative, Graduate Student Council Wayne State University School of Medicine, 2003-2004. Student Representative for Cancer Biology Program Wayne State University School of Medicine, 2002-2003. Organizing Committee, DNA in Science Symposium, Wayne State University School of Medicine, 2001. Projects: Development and characterization of MCF-10 cells as a 3D in vitro model system of breast cancer progression. MCF-10, 3D model system of breast cancer progression was used in subsequent projects: Screening protease inhibitors for an effect on the development of breast cancer. Microarray analysis of altered protease expression during breast cancer progression. Proteolytic degradation of E-cadherin and its role in breast cancer progression. Testing protease activity based probes.

  • Experience

    • Fox Chase Cancer Center

      Jan 2006 - Nov 2009

      Projects: Discovery of natural substrates and binding proteins for FAP to elucidate its function. Analysis of FAP function in the tumor stromal environment using an in vitro model system. Examination of the effect of the tumor stroma on chemoresistance. Screening cancer therapeutics either activated by FAP or directly inhibiting FAP. Development of a tissue specific FAP transgenic mouse.

      • Intern-Office of Corporate Alliances

        Aug 2009 - Nov 2009
      • Post Doctoral Associate

        Jan 2006 - Aug 2009
    • MedImmune

      Nov 2009 - May 2017
      Scientist I

      • Pharmacology lead for late stage projects: involved in planning, analysis, and presentation to the team. Chair Joint Pharmacology meeting under research collaboration.• Represent Research at cross-functional Joint Steering Committee, Product Development Team and Translational Sciences Sub-team meetings.• Develop optical imaging capabilities to support the oncology pipeline.• Initiate and manage external collaborations.• Management of Industrial Placement Students and FP7 Post-Doctoral Associate. Show less

    • AstraZeneca

      May 2017 - Oct 2019
      Scientist II

      • Research project lead: Cross-functional collaboration to deliver therapeutics through pipeline, target validation, stakeholder management• Pharmacology lead for oncology projects: involved in planning, analysis, and presentation to the team. Chair Joint Pharmacology meeting under research collaboration.• Represent Research at cross-functional Joint Steering Committee, Product Development Team and Translational Sciences Sub-team meetings.• Develop optical imaging capabilities to support the oncology pipeline.• Initiate and manage external collaborations.• Management of Industrial Placement Students Show less

    • Traveling

      Oct 2019 - May 2020
      Sabbatical
    • LabGenius

      Jan 2021 - Apr 2022
      Senior Sceintist

      LabGenius is the first biopharmaceutical company developing next generation protein therapeutics using a machine learning-driven evolution engine (EVA™).Our protein engineering platform integrates several bleeding edge technologies from the fields of machine learning, synthetic biology and robotics.Key responsibilities: Lead strategic pipeline development: target review, identification, and proposals Initiate and manage CRO studies: target validation and pre-clinical activities Initiate and manage relationship with KOLs Disease biology assessment of business development opportunities Mentoring junior colleagues Show less

    • F-star Therapeutics, Inc.

      Apr 2022 - Jun 2023
      Senior Scientist

      Translational sciences lead for early stage clinical programs.

    • InvoX Pharma Limited

      Jun 2023 - Sept 2024
      Principal Scientist

      Translational sciences lead for early stage clinical programs: o Define the translational sciences strategy in line with 5Rs for drug development. Target validation, PK/PD modeling, safety, dose and schedule selection (FIH and RP2D), biomarker strategy, patient selection strategy. o Delivery of key PK/PD and biomarker datasets with recommendations to support clinical project milestonesProject lead for preclinical project transitioning to the clinic: due diligence and gap analysis, recommended plan to support IND and work with team to deliver on plan, stakeholder management, collaboration with affiliate company Show less

  • Licenses & Certifications

    • Home Office licence modules 1-4

      Home Office
  • Honors & Awards

    • Awarded to Stefanie Mullins
      Best in Show-Judges Choice Poster Award MedImmune Cambridge Science Fair, 2016. - Jun 2016
    • Awarded to Stefanie Mullins
      AstraZeneca 2011 CEO award AstraZeneca Mar 2012
    • Awarded to Stefanie Mullins
      Recognition of Exceptional Academic and Research Accomplishments 2004 and 2005 - 2004
    • Awarded to Stefanie Mullins
      Selected young investigator at Aspen Cancer Conference - 2003
    • Awarded to Stefanie Mullins
      Travel Award 3rd IPS meeting, Nagoya, Japan - 2003
    • Awarded to Stefanie Mullins
      Dean's list 1998-1999 Grand Valley State University 1998