Experience

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  Psychopharmacology department, university of bristol

  Jan 1995 - Jan 1996

  Summer student

  Awarded John Lewis bursary to study imadazoline receptors with Alan Hudson.

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  Glaxo institute of applied pharmacology

  Oct 1996 - Jan 2000

  Phd student

  Functional characterisation of P2X7 receptors (mouse, human and rat). Used in vitro techniques such as dye/radiolabel uptake assays, electrophysiology and site-directed mutagenesis of cloned receptors. Supervised by Anton Michel.

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  Astrazeneca r&d charnwood

  Jan 2000 - Mar 2011

  Senior research scientist

  • Extensive in vivo technical skills in multiple rodent models• Excellent disease model knowledge across respiratory and inflammation areas with a good ability to monitor model consistency and trouble shoot issues• Expertise in a broad range of in vitro and ex vivo assay technologies including flow cytometry, ELISA, cell culture and isolated tissue work• Proven collaborative working skills as demonstrated by cross-department, cross-site and external interactions• Good organisational skills along with the ability to manage multiple projects in a pro-active and independent manner Show less

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  Astrazeneca

  Apr 2011 - Jun 2012

  Senior scientist, cvgi

  Designed an in vivo spreadsheet for CVGI Alderley consolidating several in vivo model spreadsheets to form one master. Membership on screening data capture initiative in vivo focus group completing in vivo data contract. Department closure activities.

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  Astrazeneca r&d alderley park

  Jun 2012 - Dec 2013

  Senior scientist, safety pharmacology

  Joined Global Safety Pharmacology and rapidly gained competency in experimental work, fulfilling the project safety pharmacologist (PSP) role and developing an understanding of toxicology, FTIM and SP studies required for IMPD/IND submissions. PSP on multiple projects in US, UK and Sweden across various disease areas. Used lead biologist experience to gain insight into critical project safety questions and to design/deliver investigative safety pharmacology studies including organ bath work at various CROs and a chronic renal study for an in-licensing opportunity. Study director for safety pharmacology functional endpoints on toxicology studies with good working knowledge of GLP/GLS and experience of GEL authoring/reviewing. As the safety pharmacology renal lead was responsible for developing the global renal safety pharmacology strategy/experimental capabilities. Member of renal SKG; proposing two out of three top strategic priorities presented to GSA Leadership Team. Led the CRL GLP-renal study transition activities working to build the partnership/ mutual understanding and contributed to validation publication. Provided expert renal SP opinion & contributed to various projects in study reports and regulatory documents as well as being an invited speaker on urinary module of BSTP lecture series. Show less

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  Astrazeneca

  Oct 2013 - Jan 2022

  Led a global team of externalisation specialists, functional project managers and finance specialists within Clinical Pharmacology and Safety Sciences (CPSS). Managed a significant outsourcing budget and ensured delivery to agreed financial targets. Worked in partnership with external vendors, CROs and academic groups to deliver to agreed objectives and plans whilst enhancing existing partnerships and taking them to the next level. Chaired regular business reviews with external partners regarding performance, delivery and future strategic directions. Actively identified new opportunities for partnering to meet both the current and future business needs. Developed a long term strategy for externalisation with regards to innovative science, data science and regulatory excellence for later stage development. Worked across regions and skill groups within CPSS and with other local and global functions. By building a strong cross functional internal network I influenced and engaged stakeholders to enable project progression. Show less Led a team of externalisation specialists and functional project managers within Clinical Pharmacology and Safety Sciences (CPSS). Managed a significant outsourcing budget and ensuring delivery to agreed financial targets. Worked in partnership with external vendors, CROs and academic groups to deliver to agreed objectives and plans whilst enhancing existing partnerships and taking them to the next level. Chaired regular business reviews with external partners regarding performance, delivery and future strategic directions. Actively identified new opportunities for partnering to meet both the current and future business needs. Developed a long term strategy for externalisation with regards to innovative science, data science and regulatory excellence for later stage development. Worked across regions and skill groups within CPSS and with other local and global functions. By building a strong cross functional internal network I influenced and engaged stakeholders to enable project progression. Show less Alliance manager for strategic partership with a CRO that delivered DMPK screening data for AstraZeneca. Ensured KPIs were met and troubleshooted issues that impacted delivery of data.Maintained & updated the relevant trackers to enable KPI calculations.Ensured effective communication of outsourcing working model to all key customers in the various IMEDS. Point of contact for DSM studentships, collaborations and consortia. Coordinated links with procurement, finance and SP&A to ensure contracts/POs in place. Show less

  • Director Alliance and Project Management, Clinical Pharmacology and Safety Sciences

    Aug 2021 - Jan 2022

  • Head of Alliance and Project Management, Clinical Pharmacology and Safety Sciences

    Sept 2017 - Aug 2021

  • Externalisation Lead

    Oct 2013 - Sept 2017
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  Exscientia

  Jan 2022 - Jun 2024

  Led a global team of alliance, scientific portfolio and CRO managers to deliver the Exscientia discovery scientific portfolio.Championed development of individuals in the team, providing coaching and support to enable individuals to independently deliver to their potential and the business needs.Created CRO management team with accountability to support all discovery outsourcing activities utilising efficient ways of working with a focus on Coordinated scientific project governance committee and held scientific teams and ac-suute members to account for delivery and review of project delivery on accordance with science, budget and timelines.Accoubtable for support of preclinical outsourcing strategy. Show less

  • Executive Director Head of Scientific Business Operations

    Mar 2024 - Jun 2024

  • Executive Director Head of Portfolio Management

    May 2023 - Feb 2024

  • Discovery Chief of Staff

    Jul 2022 - May 2023

  • Director of CRO Management

    Jan 2022 - Jul 2022
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  Stealth startup

  Jul 2024 - Sept 2024

  Independent consultant

  Supporting a stealth start up biotech in neuroscience by providing project management and outsourcing expertise.

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  Pharmaron

  Sept 2024 - now

  Senior director, integration partnerships