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Mirco Lorenzon

Mirco Lorenzon

MSc Student

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location of Mirco LorenzonO'connor, Australian Capital Territory, Australia

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  • Timeline

  • About me

    PhD candidate at the Australian National University - protein engineering - antibodies purification - synthetic biology

  • Education

    • Istituto Superiore statale "Giorgi-Fermi"- sede IT Enrico Fermi

      2009 - 2014
      Diploma Istituto Tecnico e Professionale Perito Industriale e capotecnico- spec. chimico

    • Rijksuniversiteit Groningen

      2019 - 2019
      Master trainesheep Biotechnology

      Activities and Societies: Master traineeship In this master traineeship I contributed to shedding light on mechanisms regulating the cellular location and function of a basic amino acid transporter in yeast; in particular, I have studied by mutational scanning approach the role played by the extracellular loop regions of this secondary transporter using several approaches: sequentially mutation, fluorescence microscopy, and transport assays to study the functionality/kinetic properties of the transporter.

    • Università degli Studi di Padova

      2017 - 2019
      Master's degree Industrial Biotechnologies 110/110 cum Laude

      Class: LM-8 - Industrial Biotechnologies

    • Università degli Studi di Padova

      2014 - 2017
      Bachelor's degree Biotechnologies 101/110

    • The Australian National University

      2021 - 2024
      Doctor of Philosophy - PhD Engineering and Optimizing Enzymes for Industry

      My current PhD projects fall under the “Engineering and Optimizing Enzymes for Industry” theme. The main project aims to engineer and optimize the staphylococcus aureus protein A (Spa)-based chromatography for the effective and affordable purification of immunoglobins” for industrial purposes exploiting different protein engineering techniques in order to obtain a more stable mutant of protein A. In addition to this primary project, I will be involved in related collaborations (through the… Show more My current PhD projects fall under the “Engineering and Optimizing Enzymes for Industry” theme. The main project aims to engineer and optimize the staphylococcus aureus protein A (Spa)-based chromatography for the effective and affordable purification of immunoglobins” for industrial purposes exploiting different protein engineering techniques in order to obtain a more stable mutant of protein A. In addition to this primary project, I will be involved in related collaborations (through the ARC Centre of Excellence in Synthetic Biology). The first is to investigate the use of Vibrio natriegens-based expression systems for the secretion of engineered chitin-degrading enzymes. The second will investigate microbial adaptation to polyurethane (PU) utilization/degradation and using laboratory-based directed evolution with systems biology approaches to mine and engineer for PU biodegradation pathway enzymes. Show less

  • Experience

    • Rijksuniversiteit Groningen

      Mar 2019 - Dec 2019
      MSc Student

      In this master traineeship I contributed to shedding light on mechanisms regulating the cellular location and function of a basic amino acid transporter in yeast; in particular, I have studied by mutational scanning approach the role played by the extracellular loop regions of this secondary transporter using several approaches: sequentially mutation, fluorescence microscopy, and transport assays to study the functionality/kinetic properties of the transporter.

    • Università degli Studi di Padova

      Apr 2020 - May 2020
      Assistant in practical training activities for students

      I worked as an assistant in practical training activities for students for a teaching course of Professor Francesco Filippini ("Informatics and Bioinformatics", for 3rd-year students in the Biotechnologies program), which was held by remote teaching via online conferencing systems (http://www.bio.unipd.it/corsibt/)

    • Università degli Studi di Padova

      Feb 2021 - Jun 2021
      University researcher in Biocatalysis

      Proteins production for Industrial purposes

    • The Australian National University

      Feb 2023 - now

      My current PhD projects fall under the “Engineering and Optimizing Enzymes for Industry” theme. The main project aims to engineer and optimize the staphylococcus aureus protein A (Spa)-based chromatography for the effective and affordable purification of immunoglobins” for industrial purposes exploiting different protein engineering techniques in order to obtain a more stable mutant of protein A. In addition to this primary project, I will be involved in related collaborations (through the ARC Centre of Excellence in Synthetic Biology). The first is to investigate the use of Vibrio natriegens-based expression systems for the secretion of engineered chitin-degrading enzymes. The second will investigate microbial adaptation to polyurethane (PU) utilization/degradation and using laboratory-based directed evolution with systems biology approaches to mine and engineer for PU biodegradation pathway enzymes. Show less

      • Doctoral student in protein engineering and synthetic biology

        Sept 2021 - now

      • Laboratory demostrator

        Feb 2023 - Apr 2023

  • Licenses & Certifications