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Nicole Selzer-Backus

Nicole Selzer-Backus

Student Teaching Assistant

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  • Timeline

  • About me

    Lehrerin für Chemie und Biologie an Gesamtschulen

  • Education

    • Philipps-Universität Marburg

      -
      Diplom Biologie Zoologie/Tierbiologie

      Activities and Societies: Administration of “Biomedia” web page Mollusca with ca. 130 000 species might be the most successful phylum. Species of the class gastropoda settled on land, fresh water and seawater. During my Diploma thesis project I focused on sea snail species of Trochidae and split my project in two parts. The first project concerned the working question, if concentrations of different chemical elements in the seawater do have influence on pattern, formation and coloration of sea snails. Therefore, I evaluated EDX and SEM analyses of pallium… Show more Mollusca with ca. 130 000 species might be the most successful phylum. Species of the class gastropoda settled on land, fresh water and seawater. During my Diploma thesis project I focused on sea snail species of Trochidae and split my project in two parts. The first project concerned the working question, if concentrations of different chemical elements in the seawater do have influence on pattern, formation and coloration of sea snails. Therefore, I evaluated EDX and SEM analyses of pallium and shell and TEM and LM images of pallium. Seawater tanks with different concentrations of different chemical elements were further established, in which sea snails were cultured to see a direct effect on the shell itself. Additionally, I was asking if phylogenetic analyses are still possible on morphological data, here the radula. I ranked different criteria of radula based on SEM images and calculated a putative phylogenetic tree. Show less

    • Università degli Studi del Sannio-Benevento

      2009 - 2013
      Doctor of Philosophy - PhD Computational Biology

  • Experience

    • Philipps-Universität Marburg

      Oct 2007 - Jan 2008
      Student Teaching Assistant

      Supervisor: Prof. J. SchachtnerDuties: mentoring students apprentice in working and on their own project, working with different computer software, e.g. Adobe Photoshop, GeneDoc

    • Justus Liebig Universität Gießen

      Oct 2008 - Feb 2009
      Graduate Teaching Assistant

      Supervisor: Prof. S. KölleDuties: mentoring students apprentice in working with and dissecting vertebratesSupervisor: Prof. R. BrehmDuties: mentoring students apprentice in working with microscopes and analysing histological data

    • Stazione Zoologica A Dohrn

      Apr 2009 - Jul 2013
      PhD Student

      During my PhD project I took a comparative approach using invertebrate nervous systems for experimental study has provided great leaps forward in understanding. The physiology, anatomy, and mechanisms in invertebrates are often sufficiently different to give considerable experimental advantages.To understand how processes emerge from their morphological substrates is essential to relate structure to function. A major aim is to have all the connectivity information for a nervous system so that the function can be more precisely interpreted. So far this has only been achieved in part for simple invertebrate nervous systems such as C. elegans.I have focused on the ascidian Ciona intestinalis, an invertebrate chordate which is part of the same phylum as vertebrates but sufficiently simplified to offer the possibility of an analysis from anatomy to function.Mapping of all connectivity in the Ciona larval neural network is a feasible objective (connectome). This information by itself will not be enough to allow us to understand ultimately how anatomy relates to behavior. We need to in addition understand the physiology of the connections. Putting these two pieces of information together will help to explain the emergent behavior. In vertebrates this unity is confounded by massive complexity of the nervous system (based on billions of cells with trillions of connections) and the elaborate nature of the physiology.Massive crowd sourcing annotation of serial EM sections with the new scanning block face technology may eventually enable the anatomy of even complex nervous systems to be established. However, only in ascidians with their limited numbers of neurons (100s) and connections (1000s of synapses) and simple physiology is this goal imminently achievable.Therefore, as a first step in this direction, I have applied bioinformatics and anatomical studies to produce a connectome of part of the nervous system of the solitary tunicate Ciona intestinalis. Show less

    • The Sven Lovén Centre for Marine Sciences

      Aug 2009 - Aug 2009
      Summer Research Intern

      Analysis of biotic effects on the fertility of Ciona intestinalis

    • Stazione Zoologica Anton Dohrn

      Sept 2009 - Sept 2009
      Graduate Teaching Assistant

      1st Kemali-IBRO Mediterranean School of NeuroscienceSupervisor: Dr. E. R. BrownDuties: mentoring students in working with Fluorescence microscopy and dissection invertebrates

    • Observatoire Océanologique de Banyuls sur Mer (OBS)

      Jul 2010 - Jul 2010
      Summer Research Fellow

      GRAIL – Comparison between Branchiostoma lanceolatum and Ciona intestinalis larvae neuromuscular systems using EM and immunocytochemistry

    • Stazione Zoologica Anton Dohrn

      Jul 2011 - Jul 2011
      Graduate Teaching Assistant

      2nd Kemali-IBRO Mediterranean School of NeuroscienceSupervisor: Dr. E. R. BrownDuties: mentoring students in planning and creating a project

    • Umeå University

      Jan 2014 - Dec 2015
      PostDoc Fellow

      Mycobacterium tuberculosis is a rod shaped bacteria, which causes the human diseases tuberculosis. M. marinum M and Mycobacterium bovis BCG function as model organisms for Mycobacterium and their genomes were recently sequenced. Streptomyces coelicolor is a filamentous bacterium and is established as model organisms for polar growth. Both genera Mycobacterium and Streptomyces belong to the order Actinomycetales (phylum Actinobacteria) and I investigate their relationship on proteomic level, focusing on cytoskeletal like proteins involved in growth and polarity. The aim is to visualize the spatial localization of intermediate filament like proteins in M. bovis BCG and M. marinum M to give further answers on protein function, cell stability and the mechanism behind polarity establishment and maintenance among Actinobacteria. This would further demonstrate putative protein evolution. Show less

    • IAD GmbH

      May 2017 - Jul 2017
      Projektmanagement Training and Certification

    • Bezirksregierung Düsseldorf

      Dec 2018 - now
      Lehrkraft für Naturwissenschaften

  • Licenses & Certifications

    • Prince 2 Foundation

      APMG International