
Timeline
About me
Experienced researcher in the field of metabolic drugs for effective therapeutics against aggressive carcinomas
Education

St. anne's english medium school, lonand
-S. s. c. 76.9%
A. s. d. b. dadawala jr. college, pune
2006 - 2008H.s.c. 68%
The hebrew university of jerusalem
2019 - 2026Doctor of philosophy - phd metabolism and cell fateLab: Dr. Yoav Shaul Lab, Department of Biochemistry and Molecular Biology, The Institute for Medical Research Israel - Canada (IMRIC), Faculty of Medicine, The Hebrew University - Hadassah Medical School, Jerusalem (https://www.shaullab.com/)Research Description: My doctoral research focuses on the role of metabolic processes as regulators of tumor progression.Visiting PhD Scholar: As a part of my doctoral research, I also undertook isotope labelling and tracing experiments to… Show more Lab: Dr. Yoav Shaul Lab, Department of Biochemistry and Molecular Biology, The Institute for Medical Research Israel - Canada (IMRIC), Faculty of Medicine, The Hebrew University - Hadassah Medical School, Jerusalem (https://www.shaullab.com/)Research Description: My doctoral research focuses on the role of metabolic processes as regulators of tumor progression.Visiting PhD Scholar: As a part of my doctoral research, I also undertook isotope labelling and tracing experiments to study metabolic flux at Dr. Andre Wegner's Lab at The Technical University of Braunschweig, Germany for two months (01 September, 2023 - 31 October, 2023).Teaching Experience: Alpha program instructor to mentor two high school students every year for their lab project (October 2022 - Till date) Show less

Garden city university
2008 - 2011B.sc. biotechnology 77.4%Activities and Societies: Active participation in NATIONAL SERVICE SCHEME (N. S. S. ) for a period of 2 years as N. S. S. volunteer from June 2008 - March 2010 Bachelor's Project Report: Field Study on Gene and Genotype Frequency of Autosomal and Sex – Linked Mendelian Traits in HumanLab: Department of Genetics, Garden City College, BangaloreSupervisor: Dr. Prabhakara G. S., Head of Department (HOD)Position: Undergraduate TraineeMethods and Techniques: Statistical surveyResearch Description: The objective was to study the observed phenotypic variations concerning Mendelian traits among different subjects and… Show more Bachelor's Project Report: Field Study on Gene and Genotype Frequency of Autosomal and Sex – Linked Mendelian Traits in HumanLab: Department of Genetics, Garden City College, BangaloreSupervisor: Dr. Prabhakara G. S., Head of Department (HOD)Position: Undergraduate TraineeMethods and Techniques: Statistical surveyResearch Description: The objective was to study the observed phenotypic variations concerning Mendelian traits among different subjects and calculate the occurrence of the underlying genetic frequencies responsible for the same. Show less

Fergusson college
2011 - 2013Master of science (m.sc.) biochemistry 75.45%Activities and Societies: Internship: Isolation, Purification and Characterization of Bioactive Compounds from Plant Extracts Lab: A. J. Organica Pvt. Ltd., Pune, India Supervisor: Dr. Shobhana Bhide, Scientist Position: Project Trainee Tenure: November 01, 2011 – January 31, 2012 (3 months) Research Description: The project aimed to isolate, purify and characterize plant lectin Concanavalin A (Con A) from Jack bean seeds and study its therapeutic potential against gp120 of HIV. Masters Dissertation Thesis: Network Architecture and Robustness of a Tristable Toggle Switch in Leishmania – A Synthetic Biology PerspectiveLab: Systems and Synthetic Biology Lab, NCCS, Pune, IndiaSupervisor: Dr. Shailza Singh, Scientist DPosition: Dissertation TraineeTenure: July 09, 2012 – March 30, 2013 (9 months)Research Description: The laboratory studied sphingolipid metabolism governed pathogenesis of Leishmania major. The project aimed to… Show more Masters Dissertation Thesis: Network Architecture and Robustness of a Tristable Toggle Switch in Leishmania – A Synthetic Biology PerspectiveLab: Systems and Synthetic Biology Lab, NCCS, Pune, IndiaSupervisor: Dr. Shailza Singh, Scientist DPosition: Dissertation TraineeTenure: July 09, 2012 – March 30, 2013 (9 months)Research Description: The laboratory studied sphingolipid metabolism governed pathogenesis of Leishmania major. The project aimed to computationally design a controlled synthetic genetic circuit such that it would negatively regulate the expression of parasitic target enzyme IPCS and redirect sphingolipid metabolism towards enhanced expression rate of the therapeutic enzyme SMS. The goal was to in silico study the steady state expression pattern of the genes involved in the circuit within a time frame. Thus, synthetic genetic circuit was computationally designed and steady state simulations were performed using Tinker Cell. Show less
Experience

National center for cell science
Nov 2013 - Apr 2014Project assistantProject title: STAT3 A Key Regulator and Novel Therapeutic Target in Osteopontin – Induced Tumor Growth and Angiogenesis in Breast CancerLab: Signal Transduction Lab, NCCS, PuneSupervisor: Dr. Gopal Kundu, Scientist G – Shanti Swaroop Bhatnagar AwardeeResearch Description: The project planned to investigate the angiogenic role of osteopontin in breast cancer progression. My results showed an increase in the tumour volume in NOD/SCID mice injected with osteopontin induced MCF – 7 cell line in comparison with the parental MCF – 7 cell line. Immunohistochemistry results of the respective angiogenesis specific molecules correlated with animal experiment results. We also performed cell proliferation assays to examine combinatorial effects of novel STAT3 inhibitor and tamoxifen on osteopontin induced breast tumour cell proliferation. Show less

Fergusson college
Jan 2014 - Apr 2014Visiting facultyI conducted lessons for 40 hours teach Biostatistics to M.Sc. Biochemistry students at Fergusson College, Pune.
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Advanced centre for treatment, research and education in cancer(actrec)
Jun 2014 - May 2015Project junior research fellowProject Title: Profiling the Incidence of Novel Alterations Discovered in Human Lung CancerLab: Integrated Cancer Genomics Lab, ACTREC – a research wing of Tata Memorial Hospital (TMH), Mumbai, IndiaSupervisor: Dr. Amit Dutt, Scientist F (Assistant Professor/Wellcome – DBT India Alliance Trust Intermediate Fellow)Research Description: Integrated genomic analysis performed by my peers upon integrating the data obtained from four head and neck cancer cell lines pointed out NRBP1 as novel candidate. My work focused on evaluating the oncogenic potential of this novel heterozygous truncating pseudokinase domain mutation (Q73*) within Nuclear receptor binding protein (NRBP1) gene using cellular and molecular approaches. My results strongly indicated that NT8e cell line harboring mutant NRBP1 gene is oncogenic as it drives the immortalized cells (NIH3T3) to form soft agar colonies. shRNA knockdown of mutant NRBP1 in NT8e cell line significantly inhibited anchorage – independent growth and demonstrated its essentiality for oncogenic transformation. Show less

Central food technological research institute, cheluvambe mansion, mysore.
Sept 2015 - Jul 2016Project assistant level - iiProject Title: Investigating the Roles of Lipid Pathways Governing Cell DifferentiationLab: Department of Lipid Science, CFTRI, Mysore, IndiaSupervisor: Dr. Sunny, Rupwate, Scientist FellowResearch Description: The project aimed to study the differentiation mechanism of totipotent fibroblasts cells into adipocytes by understanding roles of the intermediate signaling molecules governing its differentiation. My work involved characterization of lipid droplet biogenesis using confocal microscopy as well as cloning of the respective candidate enzymes to study their significant contribution in the formation of lipid droplets. Show less

Weizmann institute of science
Sept 2016 - Dec 2016Visiting studentProject Title: Elucidating the Function of a Structural Motif Encoded Within a NF – κB ProteinLab: Department of Biomolecular Sciences, WIS, Rehovot, IsraelSupervisor: Dr. David Wallach, Professor Emeritus Research Description: The research work involved identification of novel interacting proteins of the structural motif exclusive to a protein of NF – κB transcription factor family so as to unveil its functional significance.

The hebrew university of jerusalem
Jan 2018 - Jan 2019Research fellowProject Title: Understanding the metabolic contribution of tumor suppressor WWOX in breast cancer initiation and progressionLab: Lautenberg Center for Immunology and Cancer Research, Faculty of Medicine, The Hebrew University - Hadassah Medical School, JerusalemSupervisor: Prof. Rami Aqeilan, Full professorResearch Description: The work aimed to evaluate the metabolic phenotype of WWOX knockout in triple-negative breast cancer cells.
Licenses & Certifications

Diploma in bioinformatics (distance learning)
Eau claire institute, wisconsin, usa
Perform scientific experiments on mice
The hebrew university of jerusalemMar 2018
Huji career development club
מרכז הקריירה בעברית - huji jerusalem career centerDec 2022
Honors & Awards
- Awarded to Mayur G TannaILSSE Student Exchange Grant Israel - Lower Saxony Scholar Exchange Sep 2023 The fellowship supported my travel as a Visiting PhD Scholar at Dr. Andre Wegner's Lab, The Technical University of Braunschweig, Germany for two months (01 September, 2023 - 31 October, 2023)
- Awarded to Mayur G TannaSylvia Soyka Awards for Pancreatic Cancer Research Institute for Medical Research Israel - Canada (IMRIC), Faculty of Medicine, The Hebrew University - Hadassah Medical School, Jerusalem Jun 2022 Awarded for my extensive contribution towards pancreatic cancer during my doctoral research
- Awarded to Mayur G TannaBest Logo Award Israeli Society for Mass Spectrometry (ISMS) Sep 2019 Awarded logo design to be used as ISMS logo
- Awarded to Mayur G TannaFaculty Fellowship Faculty of Medicine, The Hebrew University - Hadassah Medical School, Jerusalem Mar 2019 Awarded to meritious students pursuing doctoral research at The Faculty of Medicine, The Hebrew University - Hadassah Ein Karem, Jerusalem
- Awarded to Mayur G TannaUniversity Rank Holder University of Pune Mar 2014 Pune University - 2nd rank holder for M.Sc. Biochemistry (2011 - 2013)
Languages
- enEnglish
- hiHindi
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