Nazareth college

Graduated in October 2018

Monash university

Specialisation: Biochemistry My project was titled: ‘Mechanism of HDAC and XIAP Inhibition in Granulosa Cell Tumours’ (GCT). Following the results of a high-throughput screen that was performed in 2021, I identified an effective class of compounds called HDAC inhibitors, which showed potential as a cancer therapeutic in synergy with Smac mimetic – the compound of interest in my lab. The main focus of this project was to preliminarily identify 1) HDAC expression in GCT, and 2) to identify… Show more Specialisation: Biochemistry My project was titled: ‘Mechanism of HDAC and XIAP Inhibition in Granulosa Cell Tumours’ (GCT). Following the results of a high-throughput screen that was performed in 2021, I identified an effective class of compounds called HDAC inhibitors, which showed potential as a cancer therapeutic in synergy with Smac mimetic – the compound of interest in my lab. The main focus of this project was to preliminarily identify 1) HDAC expression in GCT, and 2) to identify the impact of inhibiting HDAC genes in KGN cells, a model cell-line for adult GCT. I have gained experience in the following techniques:• Gel electrophoresis/ qualitative block PCR• Quantitative real-time PCR • Cell culture, counting, and treatment• RNA extraction and cDNA synthesis• Western blot• Analysis of RNA-sequencing data• Bioinformatics: pathway analysis, gene set enrichment, gene ontology• R/RStudio• Organoid culturing and imaging Show less

Rmit university

Monash university

Activities and Societies: COSMOS - Christian Orthodox Society of Monash Students: Treasurer MHHS - Monash Hellenic Students Society Double majored in physiology and pharmacology

Volunteer

Associated with Chrissie Giatrakis

Volunteer

Associated with Chrissie Giatrakis