Laura Ledesma García, Ph.D. , PMP

Laura ledesma garcía, ph.d. , pmp

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location of Laura Ledesma García, Ph.D. , PMPBrussels, Brussels Region, Belgium
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  • Timeline

  • About me

    Research Project Management | PMP®| R&D Scientist | Biotechnology, Molecular Microbiology ◾️ Belgium & Spain

  • Education

    • Universidad autónoma de madrid

      2004 - 2005
      Licentiate degree environmental sciences individual mobility grant for students. program sicue / seneca
    • Universidad pablo de olavide - cabd

      2006 - 2007
      Master sc. in biotechnology
    • Universidad pablo de olavide

      1999 - 2006
      Licentiate degree environmental sciences
    • Universidad pablo de olavide

      2006 - 2012
      Doctor of philosophy - phd microbiology, general
  • Experience

    • Universidad pablo de olavide

      Sept 2005 - Dec 2012

      ▶️ In a nutshell, to reach the PhD. status at the University Pablo de Olavide, I characterized a complex regulatory system that controlled the biodegradation pathway of a xenobiotic compound broadly found in nature. Thesis awarded with the Extraordinary Doctoral award. Besides, I also achieved several successful short-terms at the University of Zaragoza (Spain) and at the University of Saarland (Germany). ▶️ For those interested in the scientific details of the proyect, my thesis work focused on understanding the regulatory mechanisms that control a xenobiotic biodegradation pathway of the Gram– bacteria Sphingomonas macrogolitabida strain TFA. The regulatory system of this pathway is composed by a LysR-type transcriptional activator (ThnR) and the co-activator ThnY, which shows homology with ferredoxin reductases of initial dioxygenase complex of aromatic compounds degradation. In addition, the expression of the thn operons is negatively modulated by a ferredoxin (ThnA3), that avoids gratuitous induction of the metabolic pathway. I worked characterizing in vivo and in vitro how ThnY exercises its function as co-regulator, and how is established the communication between the ferredoxin and the regulatory system, by using genetic and biochemical approaches.▶️ Key words:Gene expression regulation, Bacteria, Gram-, Xenobiotic compounds, Biodegradation, complex regulatory systems.Expertise in Bacterial Genetics, Microbiology, Molecular Biology and Biochemistry, Managerial. Implementation of new methods. Show less

      • Scientist / PhD. candidate

        Sept 2006 - Dec 2012
      • Undergraduate Research Fellow

        Jul 2006 - Sept 2006
      • Undergraduate internship

        Sept 2005 - Jun 2006
    • Universität des saarlandes

      Feb 2009 - May 2009
      Short-term intership

      Heterologous expression, purification and characterization of different proteins involved in electron transfer.

    • Universidad de zaragoza

      Sept 2010 - Nov 2010
      Short-term internship

      Characterization of different proteins involved in electron transfer. Characterization of flavin and iron-sulphur cluster cofactors. Protein-protein interaction and redox assays (Stopped-flow, redox potential measurement)

    • Universidad de zaragoza

      Sept 2011 - Oct 2011
      Short-term internship

      Characterization of different proteins involved in electron transfer. Characterization of flavin and iron-sulphur cluster cofactors. Protein-protein interaction and redox assays (Stopped-flow, redox potential measurement)

    • Abengoa

      Jan 2013 - Sept 2015
      R&d scientist

      ▶️ As R&D Junior scientist in the biotech department at the multinational company Abengoa, I was part of a multidisciplinary team designing and developing enhanced tailor-made fungal enzymatic cocktails to produce 2G-bioethanol from different lignocellulosic substrates. ▶️ Scientific tasks:- Purification and characterization of native cellulolytic enzymes from fungi.- Development and performance of different enzymatic analysis.- Identification of bottlenecks in the enzymatic activity of the different proteins.- Formulation of the best-suited cocktail for each lignocellulosic substrate.▶️ Other duties:- Coordination of tasks and sampling inter- e intra-departments- Writing of SOPs, patents and reports- Presentations of our worklines to partners and superiors.- Guidance, supervision and coordination of technicians.- Implementation of new procedures.▶️ Expertise in Biochemistry, Proteomics, Biotechnology and Managerial. Show less

    • Université catholique de louvain

      Oct 2015 - Sept 2022
      Research project manager / senior postdoctoral scientist

      ▶️ Study of Quorum-sensing in Streptococcus with Biotechnological interest:Study of the quorum sensing system in streptococci (ComRS) that controls the activation of natural DNA transformation and the production of antimicrobial peptides. Key topic directly connected with the broad use of Lactic acid bacteria in the industry as starter cultures and/or probiotics for pathogenic species control.▶️ Specific Research objectives:- Study of the molecular mechanisms involved in ComR-peptide interaction and activation.- Improvement of the activation of the ComRS system for improving DNA transformation yield and antimicrobial compounds production.- Study of the ComRS systems specificity and interspecies cross-talk.- Variation of the peptide recognition capacity to recognize pathogenic streptococci in order to activate bacteriocin production in response.- Translational research for biotechnological applications.▶️ Additional tasks:- Design, Managing, tracking and conclusion of Research projects.- Contact with possible collaborators- Presentations of worklines to partners and superiors.- Guidance and supervision of Master and Technician Students- Evaluation of Research Projects- Implementation of new procedures.▶️ Key words:Lactic acid bacteria, streptococci, cell-to-cell communication, antimicrobial peptides, commensal species, pathogenic species, natural DNA transformation, horizontal gene transference, bacteriocins, biotechnology.Expertise in Leadership and Managerial, Bacterial Genetics, Microbiology, Molecular Biology, Biochemistry, Biotechnology. Show less

    • Cebe - spanish scientists in belgium

      Feb 2021 - now

      ▶️ Committee focused on designing activities for the members of the association, that bring the right tools to help them to evolve from a professional and personal point of view, and develop their professional paths.- Elaboration of planning of events for upcoming periods- Preparation of documents for funding proposals- Operational guidance and follow up of team tasks- Leading the organization of the above indicated events: ◾ Job search for science and tech professionals in Spain and Belgium (in collaboration with EURES Spain). 27th January 2022. Online ◾ Employability and Networking for Scientists. 6th April 2022. Online ◾ Tips and tricks para cuidar la salud mental en la carrera investigadora. 8th November 2022. Online ◾ Taller para Reconocimiento y Puesta en Valor de Habilidades Transferibles. 21st January 2023. Onsite, Brussels, Belgium. ◾ Creating value from your research results - Patents and spin-offs (in collaboration with the Technology Transfer Office associated to KULeuven). 21st March 2023. Onsite and online, Leuven, Belgium. ◾Gestiona tu bienestar: Claves para superar los desafíos emocionales. Double event (Part I: Workshop for Stress management; Part II: Webinar for Migratory grief management). 10th Jun 2023. Onsite and online, Brussels, Belgium. Show less

      • President

        Mar 2025 - now
      • Vice President

        Mar 2022 - Mar 2025
      • Leader of the Professional Development Committee

        Feb 2021 - Apr 2023
    • Gsk

      Sept 2022 - May 2023
      Value evidence and outcomes-vaccines

      ▶️ Project Manager in studies related to Value Evidence Generation. Neisseria and Essential Portfolio assets, Vaccines. - Coordination among complex and cross-functional processes related to the launch of products.- Organization of work stream.- Communication with internal stakeholders and vendors.- Support for elaboration of Value Evidence Plans.- Organization of meetings, including agendas, pre-reads and minutes.- Tracking deliverables, timelines and budget associated to different studies.- External experts engagement. Show less

    • Amaris consulting

      Sept 2022 - Jun 2023
      Senior consultant
    • Gsk

      Jul 2023 - now
      Associate director - technical project manager

      Technical Project manager in key priority projects (mRNA flu and mRNA flu/covid combination assets)

  • Licenses & Certifications

    • Management of protected natural areas

      Forja siglo xxi sl
      Jun 2006
    • Prochain quick start critical chain certification program

      Prochain solutions, inc.
      May 2025
    • Course for pmp certification

      Edpm, escuela de project management
      Jan 2021
    • Environmental educator

      Forja siglo xxi sl
      Jan 2005
    • Project management professional (pmp®)

      Project management institute
      Oct 2021
  • Honors & Awards

    • Awarded to Laura Ledesma García, Ph.D. , PMP
      Extraordinary Doctoral Award Pablo de Olavide University 2014
  • Volunteer Experience

    • Volunteer

      Issued by CEBE - Spanish Scientists in Belgium on Sept 2020
      CEBE - Spanish Scientists in BelgiumAssociated with Laura Ledesma García, Ph.D. , PMP
    • Teacher/Environmental Educator

      Issued by Asociación para la Defensa de la Naturaleza y los Recursos de Extremadura (ADENEX) on Aug 2007
      Asociación para la Defensa de la Naturaleza y los Recursos de Extremadura (ADENEX)Associated with Laura Ledesma García, Ph.D. , PMP
    • Teacher/Environmental and Sociocultural Educator

      Issued by Escuela de Animación Natura 2000 on Aug 2007
      Escuela de Animación Natura 2000Associated with Laura Ledesma García, Ph.D. , PMP