Experience

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  Scios nova inc

  Sept 1989 - Sept 1994

  Senior research pharmacologist

  •Implemented in vivo and in vitro models of inflammation to test leukocyte recruitment inhibitors (leumedins) for efficacy and Beta-2 integrin dependency.•Rodent evaluation of subtype-selective muscarinic antagonists for inhibition of choline derivative-induced effects as models of pulmonary disease.

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  Pfizer

  May 1995 - Sept 2005

  Senior scientist | scientist

  Had a preclinical role in developing Lyrica for fibromyalgia pain.....the most significant accomplishment of my entire research career!•Promoted to a Ph.D.-level researcher that developed, characterized, and improved in vivo rodent and rabbit models for evaluating novel alpha-2-delta ligands, NSRIs, antagonists of NMDA, MgluR5 and NK-1, and inhibitors of PDE-IV, MMP, MEK, and COX-2 for potential treatment of fibromyalgia, osteoarthritis, and/or rheumatoid arthritis. •Performed preclinical development studies to advance Lyrica to eventual NDA approval for fibromyalgia pain.•Directed activities of an Associate Scientist and temporary employees. •Appointed Department contact for animal room census projections/renovation. •Assigned to ensure team results were entered into company-wide data base. •Wrote vertebrate use forms, and served on the Institutional Animal Care and Use Committee. Show less

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  Charles river laboratories

  Sept 2005 - Sept 2013

  Research scientist

  •In vivo evaluation of novel antineoplastics from pharmaceutical/biotech clients in rodent xenograft models. •Ran client-based studies and formulated drugs for dosing, while maintaining a rapid pace with a high work load. •Led all technical aspects of the company's Inflammation TA, including validation of new models, problem solving instrumentation & assays, and interviewing/training/mentoring staff.

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  Alion science and technology

  Jul 2014 - Feb 2016

  Project manager | sr. research biologist

  • Led a team of 13 senior/associate technicians and facility staff (6 direct reports) to provide inhalation/oral toxicology research support services to the NIEHS, including their National Toxicology Program.• Laboratory operations management.• Managed client budget resources and technical development of staff.• Chaired Alion’s IACUC.• Improved information collection and necropsy processes, resulting in a better quality product delivered with documented Customer satisfaction.

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  Sobran bioscience

  Aug 2016 - Dec 2016

  Associate director

  • Directed GLP rodent toxicology contract research at the Browns Summit, NC and Baltimore, MD sites.• Successfully achieved GLP site readiness in NC within a 2-month time line.• Authored, reviewed, and maintained study protocols and associated amendments as per 21 CFR, part 58.• Ensured all deviations from protocols were documented, and reported to study director & client.• Assisted clients with formulation of their test articles.

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  Duke university school of medicine

  May 2017 - Jun 2022

  Laboratory research analyst

  As part of Duke's Clinical & Translational Science Institute within the School of Medicine, the Preclinical Translational Research Unit provided animal model support (primarily cancer) to the university and external organizations. The research unit, however, was eliminated 6/30/2022.• Served as Operations Manager for coordinating study planning and execution.• Point of contact for all IACUC-related activities.• Imaged blood flow and hemoglobin saturation in dorsal window-implanted mice.• Maintained bench skills and staff guidance. Show less

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  Chemogenics biopharma

  Aug 2022 - now

  Project manager

  Solely in charge of all in vivo studies, particularly pharmacokinetic experiments, in rodents off-site. Working to achieve PHS Assurance to bring studies on-site.