Experience

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  Istituto ortopedico rizzoli

  Mar 2017 - Jul 2017

  Bachelor researcher

  I performed my Bachelor Thesis in the RAMSES Lab/Laboratorio di Immunoreumatologia e rigenerazione tissutale. My thesis was focused on the evaluation of the inflammatory state of patient biopsies suffering from femoroacetabular impingement.My work mainly consisted in:• Patient synovia and cartilage biopsies inclusion in paraffin• Tissue sectioning using the microtome• Different histological stainings• Immunohistochemestry• Optical microscope imaging

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  Greenaltech

  Jan 2018 - Feb 2019

  My research was focused on cancer therapy and it was developed interdisciplinary within the Chemistry and Molecular Biology departments. During my experience within the company I assumed different functions:• Production of a drug delivery system based on protein nanoparticles for the encapsulation of specific bioactive compounds from microalgae• Characterization and monitorization of nanoparticles through HPLC and DLS• Freeze-driying of nanoparticles• Evaluation of the anticancer and antisenolytic effect of nanoparticles on different cell lines through protein expression analysis• Literature research for experimental design, data analysis and report writing Show less Master Thesis elaboration in the Molecular Biology Department focused on the evaluation of the effect of a bioactive compound isolated from microalgae on the mechanisms and function of a specific human nuclear receptor and a protein kinase.During my experience I worked in:• Organelle isolation from human cells• Protein extraction and quantification• Analysis of protein levels through Western Blot, immunocitochemistry and ELISA• Analysis of protein-protein interaction using FRET• Performance of different biochemical assays Show less

  • Research Assistant

    Sept 2018 - Feb 2019

  • Master Researcher

    Jan 2018 - Sept 2018
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  Dkfz german cancer research center

  Mar 2019 - Jul 2019

  R&d intern in molecular neurobiology

  Internship in the Molecular Neurobiology Division led by Prof. Ana Martin-Villalba. My project was mainly focused on the optimization and miniaturization of the Smart-seq2 protocol for single cell RNA-sequencing in the context of glioblastoma.During those months I was also working transversely in other projects that allowed me to gain experience in many different techniques:• Mice perfusion and brain isolation for neural stem cells obtention, single cell sequencing and histological analysis• Familiar with FACS and Mosquito liquid handling platform for single cell sorting and library preparation• Expansion and maintenance of different human and mouse cell cultures• Lentivirus and AAVs production• Primers and probes design for PCR and qPCR Show less

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  Universidade dos açores

  Sept 2019 - Nov 2019

  R&d intern

  I took part in an European research project within the marine biotech sector called "META-MINE: Mining the microbiomes from marine wood-digesting bivalves for novel lignocellulose depolymerizing enzymes".I carried different functions such as: • Disection of shipworms and isoation of different tissues• DNA extraction, purification and gel electrophoresis• Amplification of different genes for further species identification through DNA sequencing• Supervision of master students in practical lessons Show less

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  Ucb

  Sept 2020 - Sept 2022

  Associate scientist

  During 2 years I was part of the histology and neuroimaging team of the Neurodegeneration department, where I was involved in gene therapy projects for different diseases affecting the central nervous system.

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  Ku leuven

  Oct 2022 - now

  Phd researcher

  I am carrying on my PhD project in the Laboratory of Therapeutic and Diagnostic Antibodies (LTDA) led by Prof. Maarten Dewilde which is focused on the use of nanobodies to improve drug delivery and deposition in the brain applied to diseases affecting the central nervous system.